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Symbol
Name
ID
Ghr
growth hormone receptor
MGI:95708
Phenotype annotations related to reproductive system
Darker colors indicate more annotations
Human Phenotypes
Delayed menarche
Hypoplasia of penis
Microphallus
Disease(s) Associated with GHR
isolated growth hormone deficiency
Laron syndrome

Mouse Phenotypes
abnormal spermatid morphology
decreased prostate gland ventral lobe weight
abnormal seminal vesicle weight
decreased seminal vesicle weight
decreased corpora lutea number
decreased mature ovarian follicle number
impaired ovarian folliculogenesis
decreased testis weight
abnormal ovary physiology
abnormal testes secretion
decreased testes secretion
increased uterus weight
abnormal spermatogenesis
abnormal epididymis weight
decreased epididymis weight
delayed vaginal opening
delayed female fertility
delayed male fertility
delayed sexual maturation
delayed balanopreputial separation
long gestation period
decreased ovulation rate
prolonged diestrus
abnormal metestrus
prolonged estrous cycle
impaired luteinization
impaired embryo implantation
female infertility
decreased litter size
reduced male fertility
Availability Mouse Genotype
Ghrtm1Arge/Ghrtm1Arge
Ghrtm1Jjk/Ghrtm1Jjk

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory